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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL4
All Species:
19.7
Human Site:
Y461
Identified Species:
30.95
UniProt:
Q8WUA2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUA2
NP_624311.1
492
57225
Y461
S
N
S
H
K
S
K
Y
Q
T
D
L
Y
E
R
Chimpanzee
Pan troglodytes
XP_527529
607
69328
Y576
S
N
S
H
K
S
K
Y
Q
T
D
L
Y
E
R
Rhesus Macaque
Macaca mulatta
XP_001084421
492
57172
Y461
S
N
S
H
K
S
K
Y
Q
T
D
F
Y
E
R
Dog
Lupus familis
XP_541147
492
57155
Y461
S
N
S
H
K
S
K
Y
Q
T
D
P
Y
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXG3
492
57212
Y461
S
N
S
H
K
P
K
Y
Q
T
E
P
Y
E
R
Rat
Rattus norvegicus
NP_001101927
357
40656
K327
A
K
V
K
W
K
G
K
G
G
K
Y
T
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506397
487
56623
R457
G
Y
S
K
S
K
D
R
C
R
E
E
P
R
E
Chicken
Gallus gallus
XP_419663
478
55881
Y447
Y
S
K
H
K
D
K
Y
R
E
D
V
R
I
R
Frog
Xenopus laevis
Q6GLX7
477
54856
K439
E
E
K
S
G
K
V
K
D
A
N
M
Q
D
E
Zebra Danio
Brachydanio rerio
NP_001121802
454
52864
Q423
R
S
R
D
R
E
R
Q
K
D
K
Q
R
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651291
653
75452
R496
Q
N
E
R
R
R
S
R
S
R
D
Q
T
G
K
Honey Bee
Apis mellifera
XP_001121334
512
60307
K454
K
E
H
K
Q
K
K
K
H
D
N
E
K
K
R
Nematode Worm
Caenorhab. elegans
NP_492343
427
50388
D397
D
R
D
R
S
Y
R
D
N
N
R
D
R
R
D
Sea Urchin
Strong. purpuratus
XP_001192414
536
61906
H501
K
D
R
D
T
G
R
H
G
Y
R
D
G
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871A4
494
56481
R458
R
D
L
D
R
R
D
R
R
G
D
R
S
R
D
Conservation
Percent
Protein Identity:
100
80.8
98.7
98.1
N.A.
96.7
71.9
N.A.
77
80.8
23.5
69.7
N.A.
42.4
48.6
47.5
51.1
Protein Similarity:
100
80.8
98.9
98.7
N.A.
98.1
72.3
N.A.
86.1
89
45.7
81
N.A.
55.9
65.8
65.6
65.4
P-Site Identity:
100
100
93.3
93.3
N.A.
80
0
N.A.
6.6
40
0
13.3
N.A.
13.3
13.3
0
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
13.3
N.A.
13.3
60
20
40
N.A.
26.6
33.3
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
14
7
20
0
7
14
7
7
14
47
14
0
14
14
% D
% Glu:
7
14
7
0
0
7
0
0
0
7
14
14
0
40
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
7
0
0
0
7
7
7
0
14
14
0
0
7
7
0
% G
% His:
0
0
7
40
0
0
0
7
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
14
7
14
20
40
27
47
20
7
0
14
0
7
14
7
% K
% Leu:
0
0
7
0
0
0
0
0
0
0
0
14
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
40
0
0
0
0
0
0
7
7
14
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
14
7
0
0
% P
% Gln:
7
0
0
0
7
0
0
7
34
0
0
14
7
0
0
% Q
% Arg:
14
7
14
14
20
14
20
20
14
14
14
7
20
20
60
% R
% Ser:
34
14
40
7
14
27
7
0
7
0
0
0
7
0
7
% S
% Thr:
0
0
0
0
7
0
0
0
0
34
0
0
14
0
0
% T
% Val:
0
0
7
0
0
0
7
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
0
7
0
40
0
7
0
7
34
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _